Mae'r ffilm yn ymchwilio i hanesion llafar y rhai yr effeithiwyd arnynt fwyaf, gan roi cipolwg ar sut mae cymunedau Wsbecaidd a Karakalpak yn delio â disychiad yr Amu Darya, a sut y gwnaeth yr Undeb Sofietaidd droi Môr Aral o bedwerydd llyn mwyaf y byd i anialwch ieuengaf y byd.
Trwy straeon am golled, addasiad, a gobaith, mae River to a Missing Sea yn cynnig stori ddynol trychineb amgylcheddol.
The film delves into the oral histories of those most affected, providing an insight into how Uzbek and Karakalpak communities are dealing with the desiccation of the Amu Darya, and how the USSR turned the Aral Sea from the world's fourth largest lake into the world's youngest desert.
Through tales of loss, adaptation, and hope, River to a Missing Sea offers the human story of an environmental disaster.